Metatranscriptomic assessment of burn wound infection clearance

      Skin and soft tissue infections are frequent infections in healthcare that vary in presentation and severity. The severe forms often require surgical intervention and antimicrobial therapy and their recovery should be assessed frequently to catch treatment failures [
      • Nathwani D.
      • Dryden M.
      • Garau J.
      Early clinical assessment of response to treatment of skin and soft-tissue infections: how can it help clinicians? Perspectives from Europe.
      ]. Here, we used random sequencing of coding bacterial RNA (metatranscriptomics) and 16S rRNA gene amplicon sequencing (16S profiling) to characterize the post-treatment bacterial communities of a complicated burn wound and assess infection clearance.
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